CARBON MONOXIDE POISONING COMPLICATED BY CYANIDE POISONING See treatment indications at Carbon Monoxide Poisoning and Smoke Inhalation. RATIONALE: Carbon monoxide and cyanide poisoning frequently occur simultaneously in victims of smoke inhalation. These two agents in combination exhibit synergistic toxicity. HBO2 may have a direct effect in reducing the toxicity of cyanide and augmenting the benefit of antidote treatment. The traditional antidote for cyanide poisoning is the infusion of sodium nitrate, which creates the formation of methemoglobin. This carries the potential to impair the oxygen-carrying capacity of hemoglobin. HBO2 increase in plasma dissolved oxygen content may offer a direct benefit. Source: Hyperbaric Oxygen Therapy: A Committee Report. Undersea and Hyperbaric Medical Society. 1996 Revision. Approved Indications Air or Gas Embolism Carbon Monoxide Poisoning and Smoke Inhalation Carbon Monoxide Poisoning Complicated by Cyanide Poisoning Clostridial Myonecrosis (Gas Gangrene) Crush Injury, Compartment Syndrome, Acute Traumatic Ischemias Decompression Sickness (the "Bends") Enhancement of Healing in Selected Problem Wounds Exceptional Blood Loss (Anemia) Necrotizing Soft Tissue Infections Osteomyelitis (Refractory) Radiation Tissue Damage (Osteoradionecrosis) Skin Grafts and Flaps (Compromised) Thermal Burns Chico Hyperbaric Center Telephone: Email: Chico Hyperbaric Center Web Site Developed & Hosted by Access Now 2000. Copyright © 1999-2001. All Rights Reserved. #