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Contraindications to HBO Therapy

con-tra'-in-di-ca'-tion - a symptom or condition that makes a particular treatment inadvisable.

There are few contra-indications for HBO therapy. In fact, the medical textbook Hyperbaric Medicine Practice states, "Of all the medical treatments carried out in hospitals, hyperbaric oxygen therapy is one of the most benign (non-threatening) when it comes to side effects. The contraindications are relatively few."1

Nevertheless, there are preexisting conditions that must be taken into account when determining if HBO therapy is appropriate for a particular patient. We list the following contraindications in order of severity:

  • Absolute contraindications
  • Relative contraindications
  • Additional contraindications
Absolute Contraindications


There is only one absolute contraindication to HBO therapy: untreated pneumothorax. Pneumothorax is a condition where air or gas is trapped in the fluid membrane surrounding the lungs. Surgical relief can remove this obstacle.

Also, patients should not undergo HBO therapy if they are taking or have recently taken the following drugs:

  • Doxorubicin (Adriamycin) - A chemotherapeutic drug.
  • Disulfiram (Antabuse) - Used in the treatment of alcoholism.
  • Cis-Platinum - A cancer drug.
  • Mafenide Acetate (Sulfamylon) - Suppresses bacterial infections in burn wounds
Relative Contraindications

Relative contraindications are conditions where caution is indicated but where the conditions do not necessarily rule out HBO therapy. The medical practitioner weighs the benefits of HBO therapy against any ill effects that may occur.

Upper respiratory infections - These conditions can make it difficult for the patient to clear their ears, which can result in what is termed sinus squeeze. You can interrupt HBO treatment for a few days while the infection clears or decongestants can be used.

High fevers - In most cases the fever should be lowered before HBO treatment begins.

Seizure disorders - At the Chico Hyperbaric Center (CHC), we evaluate seizure disorders on a case-by-case basis. When CHC President, Mitchell Hoggard recently asked Hyperbaric specialist Dr. Phillip James of Scotland about treating children with cerebral palsy who suffered from seizures, Dr. James said, "It's not a problem." James went on to say that when treating a patient in a multiplace chamber, he recommends simply removing the hood of the patient experiencing the seizure, wait for the seizure to stop, then continue with the treatment. Of course, this is a very broad recommendation. A detailed and individual assessment is necessary in each case.

Emphysema with CO2 retention - This condition can lead to pneumothorax during HBO treatment (see Absolute Contraindications, above).

History of thoracic (chest) surgery - This is rarely a problem and usually not considered a contraindication. However, there is concern that air may be trapped in lesions that were created by surgical scarring. These conditions need to be evaluated prior to considering HBO therapy.

Pregnancy - Many successful HBO treatments have been completed during pregnancy without danger to the fetus. However, there is concern that exposure to HBO early in a pregnancy can increase the chance of congenital problems in the fetus. Exposure to HBO later in the pregnancy appears to have no adverse effects. Each case is evaluated individually.

Malignant disease - It was once believed that HBO therapy and the subsequent increase in oxygen could accelerate the growth of tumors. Current research indicates this is not a concern.

Additional Considerations

High blood pressure - HBO therapy acts as a vasoconstrictor because it narrows or constricts blood vessels. This results in a patient's blood pressure being raised during treatment. It is not a good idea to continue with HBO therapy if a patient's blood pressure is elevated prior to HBO treatment because the treatment itself can cause it to go even higher.

At the Chico Hyperbaric Center, blood pressure is closely monitored prior to entering the chamber to ensure that a patient's blood pressure is not already elevated. Simply, our medical staff will not clear patients for treatment if their blood pressure is too high.

Asthma - A patient with acute asthma can be at increased risk. Therefore, we evaluate asthma on a case-by-case basis.

Diabetes - HBO therapy can lower a patient's blood sugar level. We recommend that patients diagnosed with diabetes or hypoglycemia (low blood sugar) eat prior to each HBO treatment in order to maintain adequate blood sugar levels during treatment. In the case of diabetic or hypoglycemic patients, our staff tests to determine blood sugar levels prior to each HBO treatment.

Special considerations for infants - There are three considerations when treating pre-term (or premature) infants and newly born infants (neonates) with HBO therapy.

  • Retinopathy of prematurity (ROP) - This is a serious condition that can result in blindness. Although ROP is associated with premature infants with low birth weight who are not treated with HBO therapy, it is felt by some that HBO therapy itself can cause ROP in premature infants. A careful examination by an Ophthalmologist of the infant's retina is needed in order to determine the degree of vascular maturity to help assess the risks involved.
  • Bronchopulmonary dysplasia (BPD) - BPD is a serious condition. BPD can result from treating a premature infant who suffers from respiratory distress (and is being assisted with mechanical ventilation) with HBO therapy. There is much that medical science does not know about HBO therapy's effect on BPD.
  • Infant congenital heart disease - Some infants with complex congenital heart disease need additional tests such as a physical exam, chest x-ray or echocardiography (EKG) in order to access the risk of doing HBO therapy.

    1 Kindwall, Eric, M.D., Editor, "Hyperbaric Medicine Practice" 1995, P. 46.

    This article is Copyright © 1999 by the Chico Hyperbaric Center (HBOToday.com). Permission is given to reproduce it, in its entirety, and including this notice.



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