Uday Chadha, M.D., F.R.C.P. Chief of Neonatology, Ottowa Civic Hospital, Ottowa,

Canada

Etiology of Cerebral Palsy

Collaborative perinatal project followed 45,000 children for 7 years. The prevalence of CP reported was 4/1000 live births.

Birth asphyxia is an uncommon cause of CP.

Most high-risk pregnancies resulted in neurologically normal children.

Only prom, chorioamnionitis and congenital malformation contributed to the increase of CP.¹

Maternal mental retardation, birth weight less than 2001 grams and fetal malformation were leading predictors of CP.²

78 percent of children with CP did not have birth asphxia and 22 percent who did had other risk factors that may have compromised their recovery.³

Pre eclampsia and UTI were not significantly associated with CP.

Antepartum hemorrhage was associated with CP this was accounted for by preterm birth.

Congenital malformation and non CP neurological disorder were significantly associated with CP.⁴

There is a high incidence of CP in very low-birth weight-infants with 1) Higher # of days on ventilator, 2) Sepsis, and 3) Severe cranial ultra sound and abnormalities.

REFERENCES

1. Nelson Et Al. Jama SEP.20; 254(11) 1473-9
2. Nelson Et Al. N.E.J.M. 1986 JUL.10; 315 (2) 81-6
3. Torfs Et Al. J Peds 1990 APR.116(4);615-9
4. Dite Et Al. Aust. N Z J Obst. Gyn. 1998;Nov.;38(4); 377-83
5. Costello Et Al. Pediatrics 1998 Aug.102;315-22

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